Panelists provided an overview of, and shared current thinking around, four key issues related to technology-assisted learning. What do we know about learning and cognition that should be applied to the online environment? Using these principles, what are some of the most effective design, teaching and learning strategies that have been explored in professional, continuous, and corporate learning, as well as higher education? In what ways do they contribute to or change our understanding of learner centeredness? How can we use existing technologies to design effective teaching and learning experiences? What are the indicators that next-generation technologies will further support these goals?