Cyberinfrastructure has become a key enabler for scholarly research. Faculty and researchers are becoming increasingly reliant on a mix of high-performance computing and communications (HPCC) hardware, software, networking, virtual organizations, and key research computing support professionals. To help develop a greater understanding of the key campus challenges in cyberinfrastructure, NSF sponsored a workshop developed by Penn State, with assistance from Internet2, in April, 2006. This workshop brought together a combination of CIOs and high level campus technical representatives – CTOs and others with similarly broad responsibilities – to share approaches and common problems, and to strategize about ways in which they would be able to improve their respective institutions’ support for the demands of current and future research computing. Attended by almost 70 people, representing 40+ US research universities, NSF and Internet2, the workshop was well received and feedback to date indicates that it was highly valuable to the participants on several levels.